Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9823987 | 0.92 | PKM (0.52) | PKMCA1CA2MMP13MMP1 | |
| Sulfuric Acid SCHEMBL10535746 | 0.92 | PKM (0.47) | PKMCA1CA2MMP13MMP1 | |
| Sulfuric Acid SCHEMBL27922881 | 0.91 | PKM (0.50) | PKMCA1CA2MMP13MMP1 | |
| Sulfuric Acid SCHEMBL22974911 | 0.91 | RAB9A (0.52) | PKMCA1CA2MMP13MMP1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8373803 | 0.84 | KCNH2 (0.45) | PKMCA1CA2MMP13MMP1 | |
| SCHEMBL1462915 | 0.84 | CA1 (0.58) | PKMCA1CA2GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL4661603 | 0.82 | CA1 (0.55) | PKMCA1CA2GAAALDH1A1 | |
| Phosphonic Acid SCHEMBL31278123 | 0.81 | CA1 (0.44) | PKMCA1CA2MMP13MMP1 | |
| SCHEMBL3746309 | 0.81 | CA1 (0.47) | PKMCA1CA2MMP13MMP1 | |
| Sulfuric Acid SCHEMBL5676715 | 0.81 | HTT (0.47) | CA1CA2MMP13MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0172697-B1 | Octahydro-oxazolo[4,5-g]quinolines | ELI LILLY AND COMPANY (US) | 1991-09-25 | — | — | EP | disclosed |
| US-4816373-A | SILVER HALIDE PHOTOGRAPHIC LIGHT SENSITIVE MATERIAL | MITSUBISHI PAPER MILLS, LTD. (JP) | 1989-03-28 | — | — | US | disclosed |
| US-4698347-A | HYPOTENSIVE AGENTS, ANTIDEPRESSANTS, SEXUAL DISFUNCTION, PARKINSONS DISEASE | ELI LILLY AND COMPANY (US) | 1987-10-06 | — | — | US | disclosed |
| US-4659832-A | REACTING UREA (OR ISOUREA) WITH 6-OXO-BROMO-QUINOLINE | ELI LILLY AND COMPANY (US) | 1987-04-21 | — | — | US | disclosed |
| EP-0172697-A2 | Octahydro-oxazolo[4,5-g]quinolines | ELI LILLY AND COMPANY (US) | 1986-02-26 | — | — | EP | disclosed |