Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824201 | 0.93 | CHRM5 (0.55) | CHRM5ADRA2CPRMT3CARM1PRMT6 | |
| SCHEMBL9824977 | 0.93 | CHRM5 (0.55) | CHRM5ADRA2CPRMT3CARM1PRMT6 | |
| SCHEMBL24724446 | 0.79 | CHRM5 (0.47) | CHRM5ADRA2CACHE | |
| SCHEMBL20329800 | 0.78 | CHRM5 (0.50) | CHRM5ADRA2CACHESMN1; SMN2NCF1 | |
| SCHEMBL9823982 | 0.77 | ALOX15 (0.46) | CHRM5ADRA2CPRMT3CARM1PRMT6 | |
| SCHEMBL19155633 | 0.77 | CHRM5 (0.59) | CHRM5ADRA2CACHESMN1; SMN2NCF1 | |
| SCHEMBL9824505 | 0.76 | ALOX15 (0.41) | CHRM5ADRA2CPRMT3CARM1PRMT6 | |
| SCHEMBL24724537 | 0.76 | CHRM5 (0.44) | CHRM5ADRA2CGNAI3GNAO1GNAI1 | |
| SCHEMBL23598134 | 0.76 | CHRM5 (0.64) | CHRM5ADRA2CACHESMN1; SMN2MAPT | |
| SCHEMBL14469252 | 0.76 | CHRM5 (0.58) | CHRM5ADRA2CACHESMN1; SMN2NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273239-B1 | CONDENSED DIAZEPINONES, PROCESSES FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1991-03-06 | — | — | EP | disclosed |
| US-4873236-A | BRADYCARDIAL AGENTS | DR. KARL THOMAE GMBH (DE) | 1989-10-10 | — | — | US | disclosed |
| EP-0273239-A1 | Condensed diazepinones, processes for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |