Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 5/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9824331 | 0.85 | SLC2A1 (0.53) | SLC2A1ACACBMTNR1AMTNR1BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL30357966 | 0.84 | SLC2A1 (0.52) | SLC2A1ACACBMTNR1AMTNR1BSIGMAR1 | |
| SCHEMBL9824451 | 0.81 | SLC2A1 (0.52) | SLC2A1ACACBMTNR1AMTNR1BSIGMAR1 | |
| SCHEMBL10411870 | 0.81 | MTNR1A (0.45) | SLC2A1ACACBMTNR1AMTNR1BSIGMAR1 | |
| SCHEMBL9825118 | 0.80 | SLC2A1 (0.43) | SLC2A1MTNR1AMTNR1BCASRSIGMAR1 | |
| SCHEMBL9825013 | 0.78 | CYP1A1 (0.44) | SLC2A1CASRSIGMAR1HTR1AADRA2B | |
| SCHEMBL9824303 | 0.78 | CYP1A1 (0.44) | SLC2A1CASRSIGMAR1HTR1AADRA2B | |
| SCHEMBL9824993 | 0.78 | CYP1A1 (0.44) | SLC2A1CASRSIGMAR1HTR1AADRA2B | |
| Fumaric Acid SCHEMBL10690449 | 0.74 | SLC2A1 (0.40) | SLC2A1MTNR1AMTNR1BCASRSIGMAR1 | |
| SCHEMBL10412812 | 0.74 | HTR2A (0.55) | HTR1AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250254-B1 | CIS & TRANS STILBENES AND THEIR COMPOSITION FOR THE TREATMENT OF HYPERTENSION | McNeilab, Inc. (US) | 1991-06-19 | — | — | EP | disclosed |
| EP-0250254-A1 | Cis & trans stilbenes and their composition for the treatment of hypertension | McNeilab, Inc. (US) | 1987-12-23 | — | — | EP | disclosed |