Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210269 | 0.91 | HTT (0.47) | SLC2A1KCNH2ACACBSMN1; SMN2MTNR1A | |
| SCHEMBL9824331 | 0.88 | SLC2A1 (0.53) | SLC2A1ACACBSIGMAR1SMN1; SMN2MTNR1A | |
| Hydrochloric Acid SCHEMBL30357966 | 0.87 | SLC2A1 (0.52) | SLC2A1ACACBSIGMAR1SMN1; SMN2MTNR1A | |
| SCHEMBL7320574 | 0.85 | SLC2A1 (0.50) | SLC2A1SIGMAR1SMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL7318305 | 0.82 | SMPD1 (0.43) | ACACBSIGMAR1ALDH1A1 | |
| SCHEMBL9824587 | 0.81 | SLC2A1 (0.45) | SLC2A1ACACBSIGMAR1MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL7349845 | 0.80 | MEN1 (0.43) | KCNH2ACACBSMN1; SMN2ALDH1A1 | |
| SCHEMBL10411870 | 0.80 | MTNR1A (0.45) | SLC2A1ACACBSIGMAR1MTNR1AMTNR1B | |
| Oxalic Acid SCHEMBL7318269 | 0.79 | PTGES (0.46) | ACACBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9825369 | 0.79 | KCNH2 (0.50) | SLC2A1KCNH2SIGMAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250254-B1 | CIS & TRANS STILBENES AND THEIR COMPOSITION FOR THE TREATMENT OF HYPERTENSION | McNeilab, Inc. (US) | 1991-06-19 | — | — | EP | disclosed |
| EP-0250254-A1 | Cis & trans stilbenes and their composition for the treatment of hypertension | McNeilab, Inc. (US) | 1987-12-23 | — | — | EP | disclosed |