Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30357966 | 0.99 | SLC2A1 (0.52) | SLC2A1SIGMAR1MTNR1AMTNR1BACACB | |
| SCHEMBL9824451 | 0.88 | SLC2A1 (0.52) | SLC2A1SIGMAR1MTNR1AMTNR1BACACB | |
| SCHEMBL9824587 | 0.85 | SLC2A1 (0.45) | SLC2A1SIGMAR1MTNR1AMTNR1BACACB | |
| SCHEMBL10411870 | 0.83 | MTNR1A (0.45) | SLC2A1SIGMAR1MTNR1AMTNR1BACACB | |
| SCHEMBL10738517 | 0.80 | SIGMAR1 (0.42) | SIGMAR1MTNR1AMTNR1BACACBPTGES | |
| SCHEMBL9210269 | 0.79 | HTT (0.47) | SLC2A1MTNR1AMTNR1BACACBMEN1 | |
| Oxalic Acid SCHEMBL10576933 | 0.77 | PTGES (0.54) | SLC2A1ACACBMEN1KMT2APTGES | |
| SCHEMBL10412812 | 0.77 | HTR2A (0.55) | — | |
| SCHEMBL9824898 | 0.77 | SLC2A1 (0.50) | SLC2A1SIGMAR1MEN1KMT2AHTT | |
| SCHEMBL9824627 | 0.77 | SLC2A1 (0.50) | SLC2A1SIGMAR1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4742084-A | Aralykyl (arylethynyl)aralkyl amines and their use as vasodilators and antihypertensives | MCNEILAB, INC. (US) | 1988-05-03 | — | — | US | claimed |
| US-4661635-A | ANTIARRHYTHMIA AGENTS | MCNEILAB, INC. (US) | 1987-04-28 | — | — | US | claimed |
| EP-0250254-B1 | CIS & TRANS STILBENES AND THEIR COMPOSITION FOR THE TREATMENT OF HYPERTENSION | McNeilab, Inc. (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4742084-A | Aralykyl (arylethynyl)aralkyl amines and their use as vasodilators and antihypertensives | MCNEILAB, INC. (US) | 1988-05-03 | — | — | US | disclosed |
| EP-0250254-A1 | Cis & trans stilbenes and their composition for the treatment of hypertension | McNeilab, Inc. (US) | 1987-12-23 | — | — | EP | disclosed |
| US-4661635-A | ANTIARRHYTHMIA AGENTS | MCNEILAB, INC. (US) | 1987-04-28 | — | — | US | disclosed |