Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2346035 | 0.88 | ALDH1A1 (0.67) | ALDH1A1CYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL31570071 | 0.87 | ALDH1A1 (0.47) | ALDH1A1ACHEMAPTCYP2C19MEN1 | |
| SCHEMBL10628943 | 0.86 | ACHE (0.53) | ALDH1A1ACHEMAPTCYP1A2CYP2C19 | |
| SCHEMBL25037396 | 0.85 | ACHE (0.57) | ALDH1A1ACHEMAPTCYP1A2CYP2C19 | |
| SCHEMBL22057590 | 0.84 | ALDH1A1 (0.59) | ALDH1A1ACHEMAPTCYP1A2CYP2C19 | |
| SCHEMBL31090296 | 0.84 | ALDH1A1 (0.59) | ALDH1A1ACHEMAPTCYP1A2CYP2C19 | |
| SCHEMBL8288255 | 0.84 | ACHE (0.56) | ALDH1A1ACHEMAPTCYP1A2CYP2C19 | |
| SCHEMBL25037229 | 0.84 | ACHE (0.56) | ALDH1A1ACHEMAPTCYP1A2CYP2C19 | |
| SCHEMBL30038413 | 0.84 | ACHE (0.56) | ALDH1A1ACHEMAPTCYP1A2CYP2C19 | |
| SCHEMBL3000567 | 0.84 | ACHE (0.56) | ALDH1A1ACHEMAPTCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200134-B1 | 5,6-Dihydroimidazo[2,1-b]thiazole-2-carboxamide derivatives or salts thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4910315-A | Containing a phenyl substitution | KUMIAI CHEMICAL INDUSTRY CO. (JP) | 1990-03-20 | — | — | US | disclosed |
| US-4736038-A | IMMUNOLOGY | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-04-05 | — | — | US | disclosed |
| EP-0200134-A2 | 5,6-Dihydroimidazo[2,1-b]thiazole-2-carboxamide derivatives or salts thereof | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1986-11-05 | — | — | EP | disclosed |