Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9825284 | 0.94 | ATM (0.55) | ATMADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL9824782 | 0.92 | ATM (0.54) | ATMADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL9824991 | 0.85 | ATM (0.48) | ATMADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL9824662 | 0.83 | ATM (0.44) | ATMADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL7291953 | 0.83 | ATM (0.43) | ATMADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL9825930 | 0.82 | KMT2A (0.47) | ATMADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL9825105 | 0.82 | ATM (0.43) | ATMADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL9825259 | 0.82 | MEN1 (0.46) | ATMADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL9825202 | 0.81 | ADRB2 (0.43) | ATMADRB2ADRB1ADRB3CYP1A2 | |
| SCHEMBL9826041 | 0.81 | ADRB2 (0.43) | ATMADRB2ADRB1ADRB3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167371-B1 | DIHYDROPYRIDINE COMPOUNDS, THEIR PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |