SCHEMBL9824924

SCHEMBL9824924

CCCC(=O)Oc1ncc[nH]1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
RAB9A P51151 2/20 0.37
KMT2A Q03164 2/20 0.37
BCL9 O00512 1/20 0.37
CTNNB1 P35222 1/20 0.37
ALOX15 P16050 1/20 0.36
TBXAS1 P24557 2/20 0.35
KDM4E B2RXH2 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP19A1 P11511 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
NUDT1 P36639 1/20 0.34
TLK2 Q86UE8 1/20 0.33
NPC1 O15118 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
ESR1 P03372 1/20 0.32
PDGFRB P09619 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5060773 0.90 KMT2A (0.41) KMT2AALOX15TBXAS1KDM4ECYP1A2
SCHEMBL4060537 0.89 TBXAS1 (0.39) ALDH1A1RAB9AKMT2ATBXAS1KDM4E
SCHEMBL27361441 0.87 DGKA (0.42) KMT2AALOX15TBXAS1SMN1; SMN2
SCHEMBL11589157 0.86 TBXAS1 (0.44) ALDH1A1RAB9AKMT2ATBXAS1KDM4E
SCHEMBL6048435 0.86 SMN1; SMN2 (0.37) ALDH1A1RAB9AKMT2ATBXAS1KDM4E
SCHEMBL25475135 0.83 TBXAS1 (0.35) ALDH1A1TBXAS1KDM4E
SCHEMBL16859456 0.83 TBXAS1 (0.35) ALDH1A1TBXAS1KDM4E
SCHEMBL16859471 0.83 TBXAS1 (0.35) ALDH1A1KMT2ATBXAS1KDM4E
SCHEMBL16859449 0.81 TBXAS1 (0.37) ALDH1A1KMT2ATBXAS1KDM4E
SCHEMBL31550386 0.80 FAAH (0.47) ALDH1A1ALOX15KDM4ECYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116472041-A Deuterium-modified thienopyridone compounds 正大天晴药业集团股份有限公司 2023-07-21 CN disclosed
EP-0195414-B1 2-AZOLYLPROPIONATE DERIVATIVES AND FUNGICIDES CONTAINING THE SAME SDS Biotech K.K. (JP) 1991-02-27 EP disclosed
US-4767752-A Imidazolyl or triazolyl substituted propionate derivative and nonmedical fungicide containing the same S.D.S. BIOTECH K.K. (JP) 1988-08-30 US disclosed
EP-0195414-A2 2-Azolylpropionate derivatives and fungicides containing the same SDS Biotech K.K. (JP) 1986-09-24 EP disclosed