Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 10/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825546 | 0.84 | — | — | |
| SCHEMBL9876132 | 0.82 | — | — | |
| SCHEMBL9826194 | 0.82 | CASR (0.38) | ALDH1A1SMN1; SMN2POLBHPGD | |
| SCHEMBL9825553 | 0.81 | DCK (0.33) | ALDH1A1 | |
| SCHEMBL9875961 | 0.80 | CASR (0.35) | ALDH1A1 | |
| SCHEMBL9876138 | 0.80 | NCF1 (0.34) | SMN1; SMN2 | |
| SCHEMBL9825549 | 0.79 | — | — | |
| SCHEMBL9825922 | 0.77 | MAPT (0.41) | ALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9825060 | 0.74 | NEK1 (0.40) | HDAC4HDAC8CTSAALDH1A1 | |
| SCHEMBL9826582 | 0.74 | TDO2 (0.41) | HDAC4HDAC8CTSAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5037575-A | Photostability | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0187015-B1 | SQUARILIUM COMPOUND AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | MITSUBISHI KASEI CORPORATION (JP) | 1991-05-29 | — | — | EP | disclosed |