Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.58 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.58 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825747 | 0.90 | CYSLTR1 (0.48) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9371999 | 0.80 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9633663 | 0.80 | MTNR1A (0.38) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL8951488 | 0.80 | CYSLTR2 (0.88) | CYSLTR2CYSLTR1 | |
| SCHEMBL8951229 | 0.79 | CYSLTR1 (0.72) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL8951149 | 0.79 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL8114767 | 0.79 | PLA2G4A (0.62) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9489805 | 0.77 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9489798 | 0.77 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1PLA2G4A | |
| SCHEMBL9527465 | 0.77 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0199543-B1 | HETEROCYCLIC AMIDE DERIVATIVES | ICI AMERICAS INC. (US) | 1991-12-04 | — | — | EP | disclosed |
| EP-0199543-A2 | Heterocyclic amide derivatives | ICI AMERICAS INC. (US) | 1986-10-29 | — | — | EP | disclosed |