Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825264 | 0.86 | TDP1 (0.49) | POLBTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL8177791 | 0.82 | POLB (0.56) | POLBTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL9825688 | 0.80 | POLB (0.53) | POLBTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL9876990 | 0.80 | POLB (0.53) | POLBTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL9825038 | 0.77 | POLB (0.50) | POLBTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL9877218 | 0.77 | POLB (0.58) | POLBTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL9825783 | 0.72 | POLB (0.52) | POLBTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL10721764 | 0.72 | HPGD (0.55) | POLBCYP3A4 | |
| SCHEMBL10718302 | 0.71 | POLB (0.51) | POLBTDP1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL8167085 | 0.71 | EPHX2 (0.51) | POLBTDP1ALDH1A1LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |