Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825228 | 0.86 | POLB (0.49) | TDP1L3MBTL1POLBCYP3A4CYP2C9 | |
| SCHEMBL8177791 | 0.77 | POLB (0.56) | TDP1L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL9825688 | 0.74 | POLB (0.53) | TDP1L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL9876990 | 0.74 | POLB (0.53) | TDP1L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL9825038 | 0.72 | POLB (0.50) | TDP1L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL9877218 | 0.72 | POLB (0.58) | TDP1L3MBTL1POLBCYP3A4CYP2C9 | |
| SCHEMBL265617 | 0.70 | TDP1 (0.63) | TDP1L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL8177152 | 0.69 | LMNA (0.52) | TDP1L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL6009689 | 0.69 | TDP1 (0.61) | TDP1L3MBTL1POLBHDAC1HDAC6 | |
| SCHEMBL8173186 | 0.68 | POLB (0.50) | TDP1POLBHDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |