Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8180307 | 0.94 | LMNA (0.50) | EPHX2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8173186 | 0.82 | POLB (0.50) | KDM4EPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5394237 | 0.80 | PTGS2 (0.67) | KDM4EPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27666303 | 0.77 | TAS1R3 (0.55) | EPHX2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL27666301 | 0.77 | TAS1R3 (0.55) | EPHX2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL8177990 | 0.77 | NPC1 (0.50) | KDM4EPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3869394 | 0.77 | NPC1 (0.50) | KDM4EPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8761160 | 0.77 | NPC1 (0.50) | KDM4EPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20583509 | 0.76 | SMN1; SMN2 (0.46) | KDM4EPOLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26110369 | 0.76 | SMN1; SMN2 (0.46) | KDM4EPOLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6013836-A | PARTICULARLY ACTIVE AGAINST MOTHS AND BEETLES AND THEIR INSECT GROWTH REGULATING ACTIVITY WITHOUT ADVERSE IMPACT ON BENEFICIAL INSECTS; CROPS; FORESTRY | ROHM AND HAAS COMPANY (US) | 2000-01-11 | — | — | US | disclosed |
| US-4985461-A | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1991-01-15 | — | — | US | disclosed |