Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2088246 | 0.94 | ACMSD (0.38) | JAK2JAK1JAK3ACMSDTDP1 | |
| SCHEMBL10793933 | 0.73 | ACMSD (0.53) | JAK2JAK1JAK3ACMSDTDP1 | |
| SCHEMBL21807796 | 0.72 | AURKA (0.35) | AURKAKDRHDAC1 | |
| SCHEMBL8380044 | 0.72 | ACMSD (0.49) | ACMSDTDP1ELANEMEN1KMT2A | |
| SCHEMBL191429 | 0.72 | ACMSD (0.49) | ACMSDTDP1ELANEMEN1KMT2A | |
| SCHEMBL4790461 | 0.71 | SIGMAR1 (0.60) | — | |
| SCHEMBL1094676 | 0.70 | ACMSD (0.47) | ACMSDTDP1ELANEMEN1KMT2A | |
| SCHEMBL8360447 | 0.70 | ACMSD (0.47) | ACMSDTDP1ELANEMEN1KMT2A | |
| SCHEMBL1109740 | 0.70 | ACMSD (0.47) | ACMSDTDP1ELANEMEN1KMT2A | |
| SCHEMBL1109745 | 0.70 | ACMSD (0.47) | ACMSDTDP1ELANEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248393-B1 | METHOD FOR THE PREPARATION OF ACYLATED HETEROAROMATICS AT ZEOLITHIC CATALYSTS | BASF Aktiengesellschaft (DE) | 1991-08-07 | — | — | EP | disclosed |