Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | SLC6A1 | P30531 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15988294 | 0.88 | LTA4H (0.64) | LTA4HHTR1A | |
| SCHEMBL9692476 | 0.85 | ALDH1A1 (0.58) | HTR1ATSHRALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL9690403 | 0.84 | ALDH1A1 (0.57) | HTR1ATSHRALDH1A1LMNA | |
| SCHEMBL18898277 | 0.83 | LTA4H (0.74) | LTA4HHTR1AALDH1A1 | |
| SCHEMBL566421 | 0.78 | LTA4H (0.64) | LTA4HHTR1A | |
| SCHEMBL9825132 | 0.78 | HTT (0.48) | HTTHTR1A | |
| SCHEMBL9825129 | 0.78 | HTT (0.48) | HTTHTR1A | |
| SCHEMBL9692523 | 0.78 | HTT (0.48) | HTTHTR1A | |
| SCHEMBL9826195 | 0.78 | HTT (0.48) | HTTHTR1A | |
| SCHEMBL9826185 | 0.78 | HTT (0.48) | HTTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252005-B1 | HYDROGENATED 1-BENZOOXACYCLOALKYL-PYRIDINE CARBOXYLIC-ACID COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | claimed |