Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068437 | 0.75 | LMNA (0.40) | ALDH1A1TSHRMEN1KMT2ALMNA | |
| SCHEMBL11556911 | 0.72 | LMNA (0.53) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL21878082 | 0.72 | MAPT (0.37) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL21878083 | 0.72 | MAPT (0.37) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL22092313 | 0.71 | MEN1 (0.44) | ALDH1A1TSHRHSD17B10HTTRECQL | |
| SCHEMBL21959849 | 0.70 | ALDH1A1 (0.36) | ALDH1A1TSHRHSD17B10HTTRECQL | |
| SCHEMBL11024710 | 0.70 | LMNA (0.46) | ALDH1A1HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL28332104 | 0.69 | KMT2A (0.65) | ALDH1A1TSHRHSD17B10HTTRECQL | |
| SCHEMBL7314915 | 0.69 | ALDH1A1 (0.35) | ALDH1A1TSHRHSD17B10MEN1KMT2A | |
| SCHEMBL27793003 | 0.66 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203743-B1 | OXOTHIAZOLIDINE COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |
| US-4764514-A | COGNITIONACTIVATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |
| EP-0203743-A1 | Oxothiazolidine compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |