Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11556911 | 0.90 | LMNA (0.53) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11024710 | 0.87 | LMNA (0.46) | LMNACA12CA1CA2CA3 | |
| SCHEMBL7314915 | 0.79 | ALDH1A1 (0.35) | LMNAKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL21878083 | 0.76 | MAPT (0.37) | KMT2AMEN1ALDH1A1TP53MDM2 | |
| SCHEMBL21878082 | 0.76 | MAPT (0.37) | KMT2AMEN1ALDH1A1TP53MDM2 | |
| SCHEMBL9831013 | 0.75 | MEN1 (0.42) | LMNACA12CA1CA2CA3 | |
| SCHEMBL9825432 | 0.75 | ALDH1A1 (0.39) | LMNAKMT2AMEN1ALDH1A1TP53 | |
| SCHEMBL18874588 | 0.73 | LMNA (0.50) | LMNACA12CA1CA2CA3 | |
| SCHEMBL21959849 | 0.73 | ALDH1A1 (0.36) | LMNAKMT2AMEN1ALDH1A1CYP3A4 | |
| SCHEMBL6129180 | 0.72 | ALDH1A1 (0.46) | LMNAKMT2AALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638552-B1 | PROCESS FOR SYNTHESIZING 4-SUBSTITUTED AZETIDINONE DERIVATIVE | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-06-04 | — | — | EP | claimed |