Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 10/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9825461 | 0.99 | MTNR1A (0.41) | MTNR1AMALT1DRD2SIGMAR1LMNA | |
| SCHEMBL9825020 | 0.90 | SIGMAR1 (0.47) | MTNR1AMALT1DRD2SIGMAR1LMNA | |
| Hydrochloric Acid SCHEMBL9824976 | 0.90 | SIGMAR1 (0.46) | MTNR1AMALT1DRD2SIGMAR1LMNA | |
| SCHEMBL9692821 | 0.85 | MALT1 (0.42) | MTNR1AMALT1DRD2SIGMAR1LMNA | |
| Hydrochloric Acid SCHEMBL9692813 | 0.84 | MALT1 (0.42) | MTNR1AMALT1DRD2SIGMAR1LMNA | |
| SCHEMBL9825383 | 0.83 | MTNR1A (0.45) | MTNR1ADRD2HTR1A | |
| SCHEMBL9825802 | 0.82 | MALT1 (0.42) | MTNR1AMALT1DRD2SIGMAR1LMNA | |
| Hydrochloric Acid SCHEMBL9825109 | 0.82 | MTNR1A (0.44) | MTNR1ADRD2HTR1A | |
| SCHEMBL10513286 | 0.81 | DRD2 (0.33) | DRD2LMNAHTR2AKCNH2 | |
| SCHEMBL9825350 | 0.81 | DRD2 (0.45) | MTNR1AMALT1DRD2SIGMAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252005-B1 | HYDROGENATED 1-BENZOOXACYCLOALKYL-PYRIDINE CARBOXYLIC-ACID COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | claimed |
| EP-0252005-A1 | Hydrogenated 1-benzooxacycloalkyl-pyridine carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | claimed |