Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.66 |
| ▸ | CTSD | P07339 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | ACR | P10323 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7748621 | 0.82 | CTSD (0.68) | CTSDKMT2AMEN1MAPTGAA | |
| SCHEMBL8907799 | 0.82 | KMT2A (0.71) | SLC6A3KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL3234187 | 0.81 | CTSD (0.62) | SLC6A3CTSDKMT2AMEN1MAPT | |
| SCHEMBL10780235 | 0.81 | SLC6A3 (0.67) | SLC6A3KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL11874477 | 0.81 | PRSS1 (0.68) | SLC6A3KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL11326953 | 0.81 | CTSD (0.66) | CTSDKMT2AMEN1MAPTGAA | |
| SCHEMBL17479848 | 0.81 | CTSD (0.66) | CTSDKMT2AMEN1MAPTGAA | |
| SCHEMBL1979275 | 0.80 | SLC6A3 (0.71) | SLC6A3KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL30505635 | 0.80 | SLC6A3 (0.71) | SLC6A3KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL113040 | 0.80 | SLC6A3 (0.71) | SLC6A3KMT2AMEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |