Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 7/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 9/20 | 0.43 |
| ▸ | ITGAV | P06756 | 8/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825509 | 0.93 | TGM2 (0.58) | TGM2CYP1A2ITGB3ITGAVITGA2B | |
| SCHEMBL9825533 | 0.90 | TGM2 (0.69) | TGM2CYP1A2ITGB3ITGAVITGA2B | |
| SCHEMBL9825862 | 0.85 | CTSL (0.58) | TGM2CYP1A2ITGB3ITGAV | |
| SCHEMBL4936394 | 0.85 | TGM2 (0.75) | TGM2TACR1 | |
| SCHEMBL9825343 | 0.85 | TGM2 (0.75) | TGM2TACR1 | |
| SCHEMBL9825798 | 0.84 | CTSL (0.59) | TGM2CYP1A2 | |
| SCHEMBL9825235 | 0.83 | TGM2 (0.71) | TGM2CYP1A2ITGB3ITGAVITGA2B | |
| SCHEMBL4935845 | 0.82 | TGM2 (0.73) | TGM2TACR1 | |
| SCHEMBL4937443 | 0.82 | TGM2 (0.82) | TGM2TACR1 | |
| SCHEMBL9826302 | 0.81 | TGM2 (0.63) | TGM2CYP1A2ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237082-B1 | 3,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOLES AS TRANSGLUTAMINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1991-05-29 | — | — | EP | claimed |