Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825953 | 1.00 | POLB (0.43) | POLBALDH1A1SMN1; SMN2HTTHTR1A | |
| SCHEMBL9691996 | 0.87 | POLB (0.44) | POLBALDH1A1SMN1; SMN2HTTHTR1A | |
| SCHEMBL9825433 | 0.87 | POLB (0.44) | POLBALDH1A1SMN1; SMN2HTTHTR1A | |
| SCHEMBL9692005 | 0.87 | POLB (0.44) | POLBALDH1A1SMN1; SMN2HTTHTR1A | |
| SCHEMBL9825444 | 0.87 | POLB (0.44) | POLBALDH1A1SMN1; SMN2HTTHTR1A | |
| SCHEMBL9825765 | 0.85 | MTNR1A (0.45) | HTTHTR1AMTNR1A | |
| SCHEMBL9825726 | 0.85 | MTNR1A (0.45) | HTTHTR1AMTNR1A | |
| SCHEMBL9826865 | 0.85 | MTNR1A (0.45) | HTTHTR1AMTNR1A | |
| Hydrochloric Acid SCHEMBL9825354 | 0.84 | MTNR1A (0.44) | ALDH1A1HTTHTR1AMTNR1A | |
| Fumaric Acid SCHEMBL9825239 | 0.82 | HTT (0.42) | HTTHTR1AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252005-B1 | HYDROGENATED 1-BENZOOXACYCLOALKYL-PYRIDINE CARBOXYLIC-ACID COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | claimed |
| EP-0252005-A1 | Hydrogenated 1-benzooxacycloalkyl-pyridine carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | claimed |