Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825726 | 1.00 | MTNR1A (0.45) | MTNR1ADRD2HTTHTR1ANPC1 | |
| Hydrochloric Acid SCHEMBL9825354 | 0.99 | MTNR1A (0.44) | MTNR1ADRD2HTTHTR1ANPC1 | |
| Fumaric Acid SCHEMBL9825239 | 0.95 | HTT (0.42) | MTNR1ADRD2HTTHTR1A | |
| SCHEMBL9825765 | 0.90 | MTNR1A (0.45) | MTNR1ADRD2HTTHTR1ANPC1 | |
| SCHEMBL9825617 | 0.85 | POLB (0.43) | MTNR1AHTTHTR1A | |
| SCHEMBL9825953 | 0.85 | POLB (0.43) | MTNR1AHTTHTR1A | |
| SCHEMBL9692374 | 0.84 | HTT (0.48) | MTNR1ADRD2HTTHTR1ANPC1 | |
| SCHEMBL9692391 | 0.84 | HTT (0.48) | MTNR1ADRD2HTTHTR1ANPC1 | |
| SCHEMBL9692918 | 0.84 | HTT (0.48) | MTNR1ADRD2HTTHTR1ANPC1 | |
| SCHEMBL9692907 | 0.84 | HTT (0.48) | MTNR1ADRD2HTTHTR1ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252005-B1 | HYDROGENATED 1-BENZOOXACYCLOALKYL-PYRIDINE CARBOXYLIC-ACID COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | claimed |
| EP-0252005-A1 | Hydrogenated 1-benzooxacycloalkyl-pyridine carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | claimed |
| EP-0252005-B1 | HYDROGENATED 1-BENZOOXACYCLOALKYL-PYRIDINE CARBOXYLIC-ACID COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | disclosed |
| EP-0252005-A1 | Hydrogenated 1-benzooxacycloalkyl-pyridine carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | disclosed |