Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | DNM1L | O00429 | 3/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CPT1A | P50416 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | CPT2 | P23786 | 1/20 | 0.32 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825332 | 0.88 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL9825661 | 0.88 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL9826314 | 0.88 | MEN1 (0.39) | ALDH1A1SMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL9825754 | 0.85 | ACACB (0.40) | ALDH1A1SMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL9825542 | 0.85 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL8880068 | 0.83 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL9825810 | 0.80 | SMN1; SMN2 (0.39) | ALDH1A1SMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL9826859 | 0.80 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MEN1HPGDKMT2A | |
| SCHEMBL9827155 | 0.80 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL9825897 | 0.79 | KMT2A (0.35) | ALDH1A1SMN1; SMN2MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239815-B1 | SUBSTITUTED THIAZOLES AND OXAZOLES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1991-07-24 | — | — | EP | disclosed |