Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058440 | 0.91 | HPGD (0.64) | SMN1; SMN2HPGDABCB1CYP3A4 | |
| Hydrochloric Acid SCHEMBL8167113 | 0.90 | HPGD (0.62) | SMN1; SMN2HPGDABCB1CYP3A4 | |
| SCHEMBL9714635 | 0.88 | POLB (0.63) | ABCB1CYP3A4ALDH1A1POLBCTSD | |
| SCHEMBL9714336 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2HPGDABCB1ALDH1A1GAA | |
| SCHEMBL9714479 | 0.87 | ABCB1 (0.55) | SMN1; SMN2HPGDABCB1ALDH1A1GAA | |
| SCHEMBL9714633 | 0.84 | ALDH1A1 (0.56) | ABCB1ALDH1A1CTSD | |
| SCHEMBL10720263 | 0.81 | HPGD (0.70) | SMN1; SMN2HPGD | |
| SCHEMBL9825307 | 0.81 | HPGD (0.70) | SMN1; SMN2HPGDABCB1CYP3A4POLB | |
| SCHEMBL9714396 | 0.81 | ABCB1 (0.56) | ABCB1CYP3A4LMNANPSR1 | |
| SCHEMBL10718593 | 0.81 | ABCB1 (0.51) | SMN1; SMN2HPGDABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463269-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-13 | — | — | EP | disclosed |
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |