Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9714340 | 0.92 | ABCB1 (0.49) | SMN1; SMN2HPGDABCB1 | |
| SCHEMBL9825684 | 0.88 | SMN1; SMN2 (0.64) | SMN1; SMN2HPGDPOLBABCB1CTSD | |
| SCHEMBL9714635 | 0.85 | POLB (0.63) | POLBABCB1CTSDALDH1A1 | |
| SCHEMBL9714479 | 0.85 | ABCB1 (0.55) | SMN1; SMN2HPGDPOLBABCB1ALDH1A1 | |
| SCHEMBL9714633 | 0.82 | ALDH1A1 (0.56) | ABCB1CTSDALDH1A1 | |
| SCHEMBL9557448 | 0.80 | CTSD (0.40) | SMN1; SMN2HPGDCTSDALDH1A1GAA | |
| SCHEMBL5058440 | 0.80 | HPGD (0.64) | SMN1; SMN2HPGDABCB1 | |
| Hydrochloric Acid SCHEMBL8167113 | 0.79 | HPGD (0.62) | SMN1; SMN2HPGDABCB1 | |
| SCHEMBL9714396 | 0.79 | ABCB1 (0.56) | ABCB1 | |
| SCHEMBL9557291 | 0.78 | TP53 (0.38) | SMN1; SMN2HPGDCTSDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0245950-B1 | INSECTICIDAL N-SUBSTITUTED-N' - SUBSTITUTED-N, N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1992-06-17 | — | — | EP | disclosed |
| EP-0236618-B1 | INSECTICIDAL N'-SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |