Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825555 | 0.90 | TGM2 (0.38) | MMP9MMP8SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9825400 | 0.89 | L3MBTL1 (0.33) | MMP9MMP8SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9826287 | 0.84 | SLC7A5 (0.37) | L3MBTL1NPSR1MLYCDPOLBSMN1; SMN2 | |
| SCHEMBL9825868 | 0.83 | L3MBTL1 (0.36) | MEN1CYP1A2CYP2C19KMT2AL3MBTL1 | |
| SCHEMBL9825800 | 0.80 | IARS1 (0.37) | MEN1CYP2C19KMT2AL3MBTL1ITGB3 | |
| SCHEMBL9825651 | 0.79 | HDAC3 (0.32) | MMP9MMP8SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9825346 | 0.76 | TGM2 (0.38) | L3MBTL1ITGB3ITGA2BPOLBSMN1; SMN2 | |
| SCHEMBL4936405 | 0.76 | TGM2 (0.38) | L3MBTL1ITGB3ITGA2BPOLBSMN1; SMN2 | |
| SCHEMBL4935929 | 0.74 | TGM2 (0.40) | NPSR1MLYCDPOLBALDH1A1LMNA | |
| SCHEMBL9826251 | 0.73 | L3MBTL1 (0.37) | MEN1CYP1A2CYP2C19KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237082-B1 | 3,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOLES AS TRANSGLUTAMINASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1991-05-29 | — | — | EP | disclosed |
| US-4929630-A | SKIN DISORDERS, ACNE, 4,5-DIHYDROISOOXAZOLE PEPTIDES | SYNTEX (U.S.A.) INC. (US) | 1990-05-29 | — | — | US | disclosed |
| US-4912120-A | Containing amine and amide substitution | SYNTEX (U.S.A.) INC. (US) | 1990-03-27 | — | — | US | disclosed |