Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.45 |
| ▸ | FNTA | P49354 | 12/20 | 0.36 |
| ▸ | FNTB | P49356 | 12/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826348 | 0.81 | ALDH1A1 (0.41) | GPR35KMT2AALDH1A1HSD17B10 | |
| SCHEMBL1760864 | 0.71 | GPR35 (0.55) | GPR35KMT2AALDH1A1 | |
| SCHEMBL2727696 | 0.71 | GPR35 (0.66) | GPR35KMT2AALDH1A1 | |
| SCHEMBL9826184 | 0.71 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL7233575 | 0.68 | GPR35 (0.52) | GPR35KMT2AALDH1A1 | |
| SCHEMBL9826280 | 0.68 | GPR35 (0.52) | GPR35KMT2AALDH1A1 | |
| SCHEMBL1760858 | 0.66 | GPR35 (0.49) | GPR35ALDH1A1HSD17B10 | |
| SCHEMBL9117738 | 0.64 | GPR35 (0.48) | GPR35ALDH1A1GRIA4 | |
| SCHEMBL9253125 | 0.64 | ALDH1A1 (0.34) | FNTAFNTBKMT2AALDH1A1HSD17B10 | |
| SCHEMBL9253128 | 0.63 | ALDH1A1 (0.33) | KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249236-B1 | N-1H-TETRAZOL-5-YL-(5-RING)-CARBOXAMIDE-DERIVATIVES, A PROCESS FOR THEIR MANUFACTURE, AND THE USE THEREOF | WARNER-LAMBERT COMPANY (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4824958-A | Process for the preparation of n-1H-tetrazol-5-yl-2-pyrrole carboxamides | WARNER-LAMBERT COMPANY (US) | 1989-04-25 | — | — | US | disclosed |
| US-4748183-A | N-1H-tetrazol-5-yl-2-thiophene carboxamides, N-1H-tetrazol-5-yl-2-pyrrole carboxamides, N-1H-tetrazol-5-yl-2-furan carboxamides, and anti-allergic and anti-inflammatory use thereof | WARNER-LAMBERT COMPANY (US) | 1988-05-31 | — | — | US | disclosed |
| EP-0249236-A1 | N-1H-Tetrazol-5-yl-(5-Ring)-carboxamide-derivatives, a process for their manufacture, and the use thereof | WARNER-LAMBERT COMPANY (US) | 1987-12-16 | — | — | EP | disclosed |