Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 6/20 | 0.33 |
| ▸ | CA1 | P00915 | 6/20 | 0.33 |
| ▸ | CA2 | P00918 | 6/20 | 0.33 |
| ▸ | CA7 | P43166 | 6/20 | 0.33 |
| ▸ | CA9 | Q16790 | 6/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825815 | 0.81 | GPR35 (0.45) | ALDH1A1HSD17B10KMT2AGPR35 | |
| SCHEMBL9826184 | 0.66 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL10374441 | 0.66 | ICAM1 (0.51) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10407265 | 0.65 | ALDH1A1 (0.57) | ALDH1A1HPGDLMNAHSD17B10CYP1A2 | |
| SCHEMBL11359017 | 0.63 | ALDH1A1 (0.50) | ALDH1A1HPGDLMNAHSD17B10CYP1A2 | |
| SCHEMBL31277120 | 0.63 | ALDH1A1 (0.55) | ALDH1A1HPGDLMNAHSD17B10CYP1A2 | |
| SCHEMBL9826281 | 0.63 | TSHR (0.39) | ALDH1A1HPGDLMNAHSD17B10KDM4E | |
| SCHEMBL6920621 | 0.61 | ALDH1A1 (0.44) | ALDH1A1HPGDLMNAHSD17B10CYP1A2 | |
| SCHEMBL10928844 | 0.61 | ALDH1A1 (0.53) | ALDH1A1HPGDLMNAHSD17B10CYP1A2 | |
| SCHEMBL17965826 | 0.61 | CA12 (0.52) | ALDH1A1HPGDLMNAHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249236-B1 | N-1H-TETRAZOL-5-YL-(5-RING)-CARBOXAMIDE-DERIVATIVES, A PROCESS FOR THEIR MANUFACTURE, AND THE USE THEREOF | WARNER-LAMBERT COMPANY (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4824958-A | Process for the preparation of n-1H-tetrazol-5-yl-2-pyrrole carboxamides | WARNER-LAMBERT COMPANY (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0249236-A1 | N-1H-Tetrazol-5-yl-(5-Ring)-carboxamide-derivatives, a process for their manufacture, and the use thereof | WARNER-LAMBERT COMPANY (US) | 1987-12-16 | — | — | EP | disclosed |