Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ALPI | P09923 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825931 | 0.91 | MPO (0.39) | MPOCYSLTR1NPC1ALPLALPI | |
| SCHEMBL9826274 | 0.88 | MPO (0.37) | MPOCYSLTR1NPC1ALPLALPI | |
| SCHEMBL9827289 | 0.88 | MPO (0.37) | MPOCYSLTR1NPC1ALPLALPI | |
| SCHEMBL9826224 | 0.88 | MPO (0.37) | MPOCYSLTR1NPC1ALPLALPI | |
| SCHEMBL9827463 | 0.86 | CISD2 (0.35) | MPOCYSLTR1ALPLL3MBTL1ALDH1A1 | |
| SCHEMBL9826223 | 0.83 | ALPL (0.36) | NPC1ALPLRAB9AALDH1A1 | |
| SCHEMBL9826617 | 0.82 | MPO (0.37) | MPOCYSLTR1NPC1ALPLALPI | |
| SCHEMBL9827083 | 0.82 | MPO (0.37) | MPOCYSLTR1NPC1ALPLALPI | |
| SCHEMBL9826206 | 0.81 | MPO (0.37) | MPOCYSLTR1NPC1ALPLALPI | |
| SCHEMBL9825976 | 0.80 | SMN1; SMN2 (0.33) | MPOCYSLTR1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249236-B1 | N-1H-TETRAZOL-5-YL-(5-RING)-CARBOXAMIDE-DERIVATIVES, A PROCESS FOR THEIR MANUFACTURE, AND THE USE THEREOF | WARNER-LAMBERT COMPANY (US) | 1991-04-24 | — | — | EP | claimed |
| US-4748183-A | N-1H-tetrazol-5-yl-2-thiophene carboxamides, N-1H-tetrazol-5-yl-2-pyrrole carboxamides, N-1H-tetrazol-5-yl-2-furan carboxamides, and anti-allergic and anti-inflammatory use thereof | WARNER-LAMBERT COMPANY (US) | 1988-05-31 | — | — | US | claimed |
| EP-0249236-A1 | N-1H-Tetrazol-5-yl-(5-Ring)-carboxamide-derivatives, a process for their manufacture, and the use thereof | WARNER-LAMBERT COMPANY (US) | 1987-12-16 | — | — | EP | claimed |