Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826207 | 0.78 | MAPK1 (0.34) | KDM4E | |
| SCHEMBL9827332 | 0.78 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL10567472 | 0.77 | — | — | |
| SCHEMBL10572170 | 0.74 | CDC7 (0.33) | KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL11564103 | 0.71 | — | — | |
| SCHEMBL8555731 | 0.69 | — | — | |
| SCHEMBL6845036 | 0.66 | — | — | |
| SCHEMBL11583412 | 0.66 | — | — | |
| SCHEMBL167563 | 0.65 | LMNA (0.39) | KDM4EALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1514052 | 0.63 | SMN1; SMN2 (0.33) | KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301613-B1 | THIAZOLE COMPOUNDS HAVING FUNGICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1991-07-10 | — | — | EP | disclosed |
| US-4889863-A | NONPHYTOTOXIC; SEEDS, SOILS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1989-12-26 | — | — | US | disclosed |
| EP-0301613-A1 | Thiazole compounds having fungicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1989-02-01 | — | — | EP | disclosed |