Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.60 |
| ▸ | TBXAS1 | P24557 | 17/20 | 0.57 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827059 | 0.85 | CYP19A1 (0.52) | CYP19A1PLA2G4A | |
| SCHEMBL11241508 | 0.84 | CYP19A1 (0.66) | CYP19A1TBXAS1PLA2G4A | |
| SCHEMBL8803260 | 0.82 | CYP19A1 (0.63) | CYP19A1TBXAS1PLA2G4A | |
| SCHEMBL9826293 | 0.82 | TBXAS1 (0.54) | CYP19A1TBXAS1 | |
| SCHEMBL9826309 | 0.82 | TBXAS1 (0.54) | CYP19A1TBXAS1 | |
| SCHEMBL9826298 | 0.82 | TBXAS1 (0.54) | CYP19A1TBXAS1 | |
| Hydrochloric Acid SCHEMBL411003 | 0.81 | CYP19A1 (0.62) | CYP19A1TBXAS1PLA2G4A | |
| Bromide SCHEMBL11242765 | 0.81 | CYP19A1 (0.62) | CYP19A1TBXAS1PLA2G4A | |
| SCHEMBL8804155 | 0.80 | PLA2G4A (0.61) | CYP19A1TBXAS1PLA2G4A | |
| SCHEMBL30023445 | 0.80 | TBXAS1 (0.66) | CYP19A1TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150892-B1 | SUBSTITUTED ALKYLIDENE IMIDAZOLES | G.D. Searle & Co. (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4837333-A | SELECTIVE INHIBITOR OF THROMBOXANE SYNTHETASE ENZYME | G. D. SEARLE & CO. (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0150892-A2 | Substituted alkylidene imidazoles | G.D. Searle & Co. (US) | 1985-08-07 | — | — | EP | disclosed |