Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.66 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240600 | 0.86 | CYP19A1 (0.60) | CYP19A1TBXAS1ALDH1A1KDM4EMAPT | |
| SCHEMBL8803260 | 0.86 | CYP19A1 (0.63) | CYP19A1PLA2G4ATBXAS1ALDH1A1MAPT | |
| Bromide SCHEMBL11242765 | 0.85 | CYP19A1 (0.62) | CYP19A1PLA2G4ATBXAS1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL411003 | 0.85 | CYP19A1 (0.62) | CYP19A1PLA2G4ATBXAS1ALDH1A1MAPT | |
| SCHEMBL11235571 | 0.85 | TBXAS1 (0.57) | CYP19A1PLA2G4ATBXAS1 | |
| SCHEMBL8804155 | 0.84 | PLA2G4A (0.61) | CYP19A1PLA2G4ATBXAS1ALDH1A1MAPT | |
| SCHEMBL9826233 | 0.84 | CYP19A1 (0.60) | CYP19A1PLA2G4ATBXAS1 | |
| SCHEMBL11248755 | 0.84 | CYP19A1 (0.57) | CYP19A1ALDH1A1KDM4EMAPT | |
| SCHEMBL11238134 | 0.84 | MEN1 (0.59) | CYP19A1TBXAS1ALDH1A1KDM4EMAPT | |
| SCHEMBL11248355 | 0.84 | CYP19A1 (0.59) | CYP19A1PLA2G4ATBXAS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |