Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATP4A | P20648 | 2/20 | 0.32 |
| ▸ | ATP4B | P51164 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827035 | 0.91 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9827149 | 0.88 | ALDH1A1 (0.37) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9826859 | 0.88 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9826486 | 0.87 | PIK3CA (0.38) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9826314 | 0.86 | MEN1 (0.39) | ALDH1A1KMT2AMEN1LMNAMAPK1 | |
| SCHEMBL9826326 | 0.86 | DRD3 (0.35) | KMT2A | |
| SCHEMBL9825897 | 0.85 | KMT2A (0.35) | ALDH1A1KMT2AMEN1NPC1LMNA | |
| SCHEMBL9827456 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL9825844 | 0.80 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8881426 | 0.80 | PPARG (0.35) | KMT2AMEN1ATP4AATP4BADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239815-B1 | SUBSTITUTED THIAZOLES AND OXAZOLES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1991-07-24 | — | — | EP | disclosed |
| EP-0239815-A1 | Substituted thiazoles and oxazoles, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1987-10-07 | — | — | EP | disclosed |