Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.30 |
| ▸ | DRD3 | P35462 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827456 | 0.94 | ALDH1A1 (0.39) | ALDH1A1ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL9825690 | 0.92 | ALDH1A1 (0.39) | ALDH1A1ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL9825905 | 0.90 | ALDH1A1 (0.38) | ALDH1A1ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL9827236 | 0.90 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AKDM4EHRH3 | |
| SCHEMBL9826186 | 0.90 | HRH3 (0.36) | ALDH1A1ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL9826520 | 0.89 | CNR2 (0.34) | MEN1KMT2AKDM4ETDP1MOGAT2 | |
| SCHEMBL9825575 | 0.88 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9826243 | 0.88 | ALDH1A1 (0.37) | ALDH1A1ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL9827035 | 0.88 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9825436 | 0.88 | PIK3CA (0.35) | ALDH1A1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239815-B1 | SUBSTITUTED THIAZOLES AND OXAZOLES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1991-07-24 | — | — | EP | disclosed |
| EP-0239815-A1 | Substituted thiazoles and oxazoles, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1987-10-07 | — | — | EP | disclosed |