Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 3/20 | 0.45 |
| ▸ | GSK3A | P49840 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826586 | 0.84 | KAT2B (0.43) | ALOX15GSK3BGSK3ANPSR1ALDH1A1 | |
| SCHEMBL9825290 | 0.74 | KMT2A (0.43) | GSK3BGSK3AMEN1KMT2ALMNA | |
| SCHEMBL9708708 | 0.74 | GSK3A (0.49) | ALOX15GSK3BGSK3ANPSR1ELANE | |
| SCHEMBL1787694 | 0.72 | — | — | |
| SCHEMBL668453 | 0.71 | TSHR (0.56) | GSK3BGSK3AELANEALDH1A1KMT2A | |
| SCHEMBL9300692 | 0.71 | GSK3A (0.46) | ALOX15GSK3BGSK3ANPSR1ELANE | |
| SCHEMBL6528311 | 0.70 | TSHR (0.50) | ALOX15GSK3BGSK3AELANEALDH1A1 | |
| SCHEMBL12635490 | 0.70 | GSK3B (0.45) | ALOX15GSK3BGSK3ANPSR1ELANE | |
| SCHEMBL5798388 | 0.70 | NPSR1 (0.62) | GSK3BGSK3ANPSR1ELANEALDH1A1 | |
| SCHEMBL10681074 | 0.70 | ALDH1A1 (0.43) | GSK3BGSK3AELANEALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1272580-A | — | — | None | — | — | JP | disclosed |
| EP-0203743-B1 | OXOTHIAZOLIDINE COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |
| JP-H01272580-A | PRODUCTION OF 4-OXO-3-(4-DIPHENYLMETHYLPIPERAZIN-1-YLCARBONYLMETHYL)THIAZOLIDINE-1,1-DIOXIDE OR ITS SALT | FUJISAWA PHARMACEUT CO LTD | 1989-10-31 | — | — | JP | disclosed |
| US-4764514-A | COGNITIONACTIVATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |
| EP-0203743-A1 | Oxothiazolidine compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |