Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9708708 | 0.75 | GSK3A (0.49) | GSK3AGSK3BKMT2AMEN1RAB9A | |
| SCHEMBL10396027 | 0.73 | MAPT (0.40) | RAB9AALDH1A1LMNAMAPK1CA12 | |
| SCHEMBL668453 | 0.72 | TSHR (0.56) | GSK3AGSK3BKMT2AELANEALDH1A1 | |
| SCHEMBL7454009 | 0.72 | ELANE (0.47) | GSK3AGSK3BKMT2AMEN1RAB9A | |
| SCHEMBL13143118 | 0.71 | GSK3A (0.58) | GSK3AGSK3BKMT2AMEN1RAB9A | |
| SCHEMBL11853714 | 0.71 | GSK3A (0.45) | GSK3AGSK3BKMT2AMEN1RAB9A | |
| SCHEMBL9826285 | 0.71 | ALOX15 (0.46) | GSK3AGSK3BKMT2AMEN1RAB9A | |
| SCHEMBL6528311 | 0.71 | TSHR (0.50) | GSK3AGSK3BKMT2AMEN1RAB9A | |
| SCHEMBL7366693 | 0.71 | TSHR (0.51) | KMT2AMEN1ALOX15ALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL4133179 | 0.71 | GSK3A (0.41) | GSK3AGSK3BKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725294-A | Novel method for synthesizing oxiracetam key intermediate ethyl 2-(2, 4-dioxopyrrolidine-1-yl) acetate | UNIV ZHEJIANG TECHNOLOGY | 2015-06-24 | — | — | CN | disclosed |
| CN-104725294-A | Novel method for synthesizing oxiracetam key intermediate ethyl 2-(2, 4-dioxopyrrolidine-1-yl) acetate | UNIV ZHEJIANG TECHNOLOGY | 2015-06-24 | — | — | CN | disclosed |
| US-5371237-A | Process for the production of 4-hydroxy-2-oxopyrrolidin-1-yl-acetamide | LONZA LTD. (CH) | 1994-12-06 | — | — | US | disclosed |
| US-5276164-A | Process for the production of 4-hydroxy-2-oxopyrrolidin-1-yl-acetamide | LONZA LTD. (CH) | 1994-01-04 | — | — | US | disclosed |
| US-4824966-A | Process for the production of 4-hydroxy-2-oxo-pyrrolidin-1-yl acetamide | LONZA LTD. (CH) | 1989-04-25 | — | — | US | disclosed |
| US-4118396-A | PYRROLIDIN-2-ONES, CNS AGENTS | I.S.F. S.P.A. (IT) | 1978-10-03 | — | — | US | disclosed |