Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827097 | 0.72 | PPARG (0.53) | PARP1HSD17B10ALOX15BRD4ALDH1A1 | |
| SCHEMBL9826530 | 0.72 | BRD4 (0.49) | USP2GAAPARP1HSD17B10ALOX15 | |
| SCHEMBL1064446 | 0.72 | KMT2A (0.62) | USP2GAAHSD17B10TP53ALDH1A1 | |
| SCHEMBL5670687 | 0.71 | ALDH1A1 (0.56) | USP2GAAPARP1HSD17B10BRD4 | |
| SCHEMBL3204956 | 0.71 | ATM (0.53) | HSD17B10POLBALDH1A1THRBMEN1 | |
| Ammonia Solution, Strong SCHEMBL20513680 | 0.69 | ATM (0.51) | HSD17B10POLBALDH1A1THRBMEN1 | |
| SCHEMBL5745711 | 0.69 | KMT2A (0.56) | USP2PARP1HSD17B10BRD4TP53 | |
| SCHEMBL9825998 | 0.69 | MAOB (0.63) | PARP1HSD17B10ALOX15BRD4POLB | |
| SCHEMBL7363237 | 0.69 | CCKAR (0.44) | USP2GAAPARP1HSD17B10ALOX15 | |
| SCHEMBL7003159 | 0.69 | PARP1 (0.74) | USP2GAAPARP1HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283036-B1 | BENZOXAZINE DERIVATIVES AND PROCESSES FOR PREPARATION THEREOF | TANABE SEIYAKU CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4824833-A | ANTIDIABETIC AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-04-25 | — | — | US | disclosed |
| EP-0283036-A1 | Benzoxazine derivatives and processes for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1988-09-21 | — | — | EP | disclosed |