SCHEMBL9826441

SCHEMBL9826441

NC(N)c1ccccc1.Nc1ccc(CCO)c(N)c1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.44
TDP1 Q9NUW8 2/20 0.33
CPN1 P15169 1/20 0.33
CPB2 Q96IY4 1/20 0.33
MAOA P21397 4/20 0.33
MAOB P27338 4/20 0.33
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DPP4 P27487 2/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL213571 0.83 CASP1 (0.39) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL29835039 0.83 CASP1 (0.39) TDP1ALDH1A1TP53CYP3A4TSHR
Hydrochloric Acid SCHEMBL8667223 0.81 CASP1 (0.38) TDP1MAOAMAOBALDH1A1TP53
SCHEMBL5275466 0.75 ALDH1A1 (0.49) F2ALDH1A1TP53PTGDR2
SCHEMBL28196249 0.72 RAD52 (0.42) TDP1ALDH1A1TP53TSHRMAPK1
SCHEMBL9173072 0.71 CASP1 (0.63) F2TDP1ALDH1A1TP53CYP3A4
SCHEMBL10890416 0.71 CASP1 (0.46) TDP1MAOAMAOBALDH1A1TP53
SCHEMBL16594580 0.71 F2 (0.78) F2TDP1MAOAMAOBALDH1A1
SCHEMBL4810383 0.71 MAOB (0.59) MAOAMAOBALDH1A1CYP3A4SMN1; SMN2
1,4-Butanediol SCHEMBL28167785 0.69 F2 (0.67) F2ALDH1A1DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0226072-B1 OXIDATION DYE CONTAINING 4-AMINO-2-AMINOMETHYL PHENOL Wella Aktiengesellschaft (DE) 1991-04-10 EP claimed