Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29835039 | 1.00 | CASP1 (0.39) | CASP1TSHRMAPTGAAHTT | |
| Hydrochloric Acid SCHEMBL8667223 | 0.98 | CASP1 (0.38) | CASP1TSHRMAPTGAAHTT | |
| SCHEMBL28196249 | 0.87 | RAD52 (0.42) | CASP1TSHRMAPTGAAHTT | |
| SCHEMBL10890416 | 0.85 | CASP1 (0.46) | CASP1TSHRMAPTGAAHTT | |
| SCHEMBL9826441 | 0.83 | F2 (0.44) | TSHRMAPK1TDP1ALDH1A1TP53 | |
| SCHEMBL29378444 | 0.82 | PRKCI (0.38) | CASP1TSHRMAPTGAAHTT | |
| SCHEMBL33767 | 0.82 | PRKCI (0.38) | CASP1TSHRMAPTGAAHTT | |
| SCHEMBL29377795 | 0.81 | CASP1 (0.42) | CASP1TSHRMAPTGAAHTT | |
| SCHEMBL1048211 | 0.81 | CASP1 (0.42) | CASP1TSHRMAPTGAAHTT | |
| SCHEMBL692702 | 0.81 | CASP1 (0.42) | CASP1TSHRMAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 766 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10383803-B2 | Dye composition using at least one coupler of meta-phenylenediamine type substituted in position 4 in a medium comprising a fatty substance, processes and device | L'OREAL (FR) | 2019-08-20 | — | — | US | claimed |
| EP-2950774-B1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 4 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | OREAL (FR) | 2018-07-25 | — | — | EP | claimed |
| EP-3096735-A1 | GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME | Combe International Ltd. (US) | 2016-11-30 | — | — | EP | claimed |
| CN-105916482-A | Gradual hair color compositions and methods of use thereof | 酷姆国际公司 | 2016-08-31 | — | — | CN | claimed |
| EP-1674075-B1 | Hair colouring process comprising a cleaning step | ORÉAL L (FR) | 2016-07-20 | — | — | EP | claimed |
| US-20150366771-A1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 4 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | L'OREAL (FR) | 2015-12-24 | — | — | US | claimed |
| WO-2015112789-A1 | GRADUAL HAIRCOLOR COMPOSITIONS AND METHODS OF USING THE SAME | COMBE INTERNATIONAL LTD. (US) | 2015-07-30 | — | — | WO | claimed |
| EP-1047375-B2 | TWO-PART HAIR DYE COMPOSITIONS CONTAINING POLYETHER POLYURETHANES AND CONDITIONING AGENTS | P & G CLAIROL INC (US) | 2013-12-11 | — | — | EP | claimed |
| US-7485155-B2 | Process for washing colored keratinous fibers with a composition comprising at least one nonionic surfactant and method for protecting the color | L'OREAL S.A. (FR) | 2009-02-03 | — | — | US | claimed |
| US-20060156478-A1 | Process for washing colored keratinous fibers with a composition comprising at least one nonionic surfactant and method for protecting the color | L'OREAL S.A. (FR) | 2006-07-20 | — | — | US | claimed |
| EP-0252351-A1 | 5-Alkoxy-2,4-diamino-alkylbenzenes and hair dyes containing same | Wella Aktiengesellschaft (DE) | 1988-01-13 | — | — | EP | claimed |
| US-4713080-A | OXIDATIVE COLORING | WELLA AKTIENGESELLSCHAFT (DE) | 1987-12-15 | — | — | US | claimed |
| EP-0226072-A1 | Oxidation dye containing 4-amino-2-aminomethyl phenol | Wella Aktiengesellschaft (DE) | 1987-06-24 | — | — | EP | claimed |
| WO-1987003475-A2 | OXIDIZING HAIR DYER BASED ON 4-AMINO-2-AMINOMETHYLPHENOLS | WELLA AKTIENGESELLSCHAFT (DE) | 1987-06-18 | — | — | WO | claimed |
| US-4661114-A | COUPLERS | WELLA AKTIENGESELLSCHAFT (DE) | 1987-04-28 | — | — | US | claimed |
| EP-0182187-A1 | Oxidative dyestuff compositions for dyeing the hair, consisting of 4-amino-2-hydroxyalkyl phenols | Wella Aktiengesellschaft (DE) | 1986-05-28 | — | — | EP | claimed |
| WO-1986002829-A1 | OXIDATION-TYPE HAIR-DYEING MEANS BASED ON 4-AMINO-2-HYDROXYALKYL-PHENOLS | WELLA AKTIENGESELLSCHAFT (DE) | 1986-05-22 | — | — | WO | claimed |
| US-4473375-A | COUPLER AND DEVELOPER FOR OXIDATION COLOR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | claimed |
| US-4452603-A | OXIDATIVE DYEING WITH 1-(B-HYDROXYALKYL)-2,4-DIAMINOBENZENE AS COUPLER | WELLA AKTIENGESELLSCHAFT (DE) | 1984-06-05 | — | — | US | claimed |
| EP-0012965-B1 | PRODUCT AND PROCESS FOR DYEING HAIR | Wella Aktiengesellschaft (DE) | 1982-08-25 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10383803-B2 | Dye composition using at least one coupler of meta-phenylenediamine type substituted in position 4 in a medium comprising a fatty substance, processes and device | FABP4, KRT18, DSG1 | CASP1 1084/4885TSHR 3818/4885MAPT 1508/4885 |
| US-20060156478-A1 | Process for washing colored keratinous fibers with a composition comprising at least one nonionic surfactant and method for protecting the color | KRT18, DSG1, DSP | CASP1 2280/4885TSHR 4481/4885MAPT 998/4885 |
| US-20150366771-A1 | DYE COMPOSITION USING AT LEAST ONE COUPLER OF META-PHENYLENEDIAMINE TYPE SUBSTITUTED IN POSITION 4 IN A MEDIUM COMPRISING A FATTY SUBSTANCE, PROCESSES AND DEVICE | FABP4, KRT18, DSG1 | CASP1 1023/4885TSHR 3878/4885MAPT 1422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.