Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.52 |
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PRKCH | P24723 | 4/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827753 | 0.83 | DAO (0.44) | KDM4EMAPKAPK2DAOERN1EP300 | |
| SCHEMBL17193036 | 0.82 | KDM4E (0.47) | KDM4EMAPKAPK2DAOERN1EP300 | |
| SCHEMBL17193008 | 0.82 | IMPDH2 (0.49) | KDM4EMAPKAPK2DAOERN1EP300 | |
| Bromide SCHEMBL20854740 | 0.81 | IMPDH2 (0.47) | KDM4EMAPKAPK2DAOERN1EP300 | |
| SCHEMBL17193035 | 0.80 | ADORA3 (0.47) | KDM4EMAPKAPK2ERN1CACNA1BCLK1 | |
| SCHEMBL9826831 | 0.78 | MAOA (0.45) | KDM4EMAPKAPK2DAOERN1KDM5A | |
| SCHEMBL9827957 | 0.77 | ERN1 (0.59) | KDM4EMAPKAPK2DAOERN1EP300 | |
| SCHEMBL15700805 | 0.76 | HASPIN (0.42) | KDM4EMAPKAPK2ERN1CACNA1BCLK1 | |
| SCHEMBL9827614 | 0.76 | MAOA (0.53) | KDM4EMAPKAPK2ERN1CLK1CDK5 | |
| SCHEMBL1651489 | 0.73 | DAO (0.50) | KDM4EMAPKAPK2DAOERN1CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182210-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-05-28 | — | — | EP | claimed |
| EP-0182210-B1 | CEPHALOSPORIN DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4742053-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0182210-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-05-28 | — | — | EP | disclosed |