Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10640275 | 0.81 | PKM (0.55) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL1807382 | 0.81 | PKM (0.55) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL28732677 | 0.81 | PKM (0.55) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL9826820 | 0.80 | RXFP1 (0.44) | PKMALDH1A1 | |
| SCHEMBL24313922 | 0.80 | PKM (0.54) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL1807384 | 0.80 | PKM (0.58) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL142264 | 0.78 | KDM4E (0.62) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL10639502 | 0.78 | PKM (0.53) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL1803675 | 0.78 | PKM (0.56) | PKMADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL14368066 | 0.77 | ADRA1D (0.56) | PKMADRA1DADRA1AADRA1BADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0205348-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-25 | — | — | EP | disclosed |
| US-4889550-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-12-26 | — | — | US | disclosed |
| US-4786314-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| US-4678498-A | PRE- AND POSTEMERGENCE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-07 | — | — | US | disclosed |
| EP-0205348-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-12-17 | — | — | EP | disclosed |