Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.79 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.79 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.79 |
| ▸ | TSHR | P16473 | 1/20 | 0.79 |
| ▸ | ACHE | P22303 | 1/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.79 |
| ▸ | BLM | P54132 | 2/20 | 0.77 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.77 |
| ▸ | ESRRG | P62508 | 4/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Procainamide SCHEMBL15914 | 0.89 | ALDH1A1 (1.00) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| SCHEMBL15741421 | 0.87 | ALDH1A1 (0.86) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| Procainamide SCHEMBL40758 | 0.87 | BLM (1.00) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| Procainamide SCHEMBL28944214 | 0.87 | ALDH1A1 (0.97) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| Procainamide SCHEMBL9614531 | 0.87 | BLM (1.00) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| Procainamide SCHEMBL23270847 | 0.86 | BLM (0.97) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| Procainamide SCHEMBL9437783 | 0.86 | BLM (0.97) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| Procainamide SCHEMBL5443536 | 0.86 | BLM (0.97) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| Procainamide SCHEMBL9618624 | 0.86 | BLM (0.97) | ALDH1A1LMNASLC22A2SLC22A1TSHR | |
| Procainamide SCHEMBL341750 | 0.86 | ALDH1A1 (0.94) | ALDH1A1LMNASLC22A2SLC22A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285284-B1 | N-PHENETHYLAMINOALKYL-BENZAMIDE ANTI-ARRHYTHMIA AGENTS | Pfizer Limited (GB) | 1991-05-15 | — | — | EP | disclosed |