Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9826867 | 0.93 | MAOA (0.46) | MAOAHIF1AEPAS1CYP3A4KDM4E | |
| SCHEMBL28171176 | 0.80 | ERN1 (0.51) | MAOACYP3A4KDM4EALDH1A1MAPT | |
| SCHEMBL9828244 | 0.77 | EP300 (0.47) | KDM4EPDGFRBPDGFRAEP300KAT2B | |
| SCHEMBL17193033 | 0.77 | ADORA3 (0.44) | HIF1ACYP3A4KDM4EALOX15ALDH1A1 | |
| SCHEMBL7622167 | 0.76 | EP300 (0.56) | HIF1AEPAS1CYP3A4KDM4EALOX15 | |
| SCHEMBL12426316 | 0.75 | MAOA (0.52) | MAOAKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL9827598 | 0.75 | MAOA (0.62) | MAOACYP3A4KDM4EALOX15ALDH1A1 | |
| SCHEMBL9827318 | 0.74 | EP300 (0.52) | KDM4EPDGFRBPDGFRAEP300KAT2B | |
| SCHEMBL17193017 | 0.73 | HIPK2 (0.44) | HIF1ACYP3A4KDM4EALOX15ALDH1A1 | |
| SCHEMBL9826933 | 0.72 | MAOA (0.63) | MAOAHIF1ACYP3A4KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182210-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-05-28 | — | — | EP | claimed |
| EP-0182210-B1 | CEPHALOSPORIN DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4742053-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0182210-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-05-28 | — | — | EP | disclosed |