Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.52 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.52 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.52 |
| ▸ | KDM5A | P29375 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 5/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828244 | 0.91 | EP300 (0.47) | EP300KAT2BKAT8KDM5AKDM4E | |
| SCHEMBL17193017 | 0.82 | HIPK2 (0.44) | EP300KAT2BKAT8KDM5AKDM4E | |
| SCHEMBL9218722 | 0.79 | EP300 (0.50) | EP300KAT2BKAT8KDM5AKDM4E | |
| SCHEMBL17193033 | 0.78 | ADORA3 (0.44) | EP300KAT2BKAT8KDM5AKDM4E | |
| SCHEMBL15700841 | 0.77 | CA12 (0.40) | EP300KAT2BKAT8KDM5AKDM4E | |
| SCHEMBL9826867 | 0.77 | MAOA (0.46) | EP300KAT2BKAT8KDM4EMAPKAPK2 | |
| SCHEMBL15056367 | 0.75 | RPS6KA3 (0.44) | EP300KAT2BKAT8KDM5AKDM4E | |
| SCHEMBL17348618 | 0.75 | EP300 (0.41) | EP300KAT2BKAT8KDM5AKDM4E | |
| SCHEMBL9826844 | 0.74 | MAOA (0.46) | EP300KAT2BKAT8KDM4EMAPKAPK2 | |
| SCHEMBL9827753 | 0.72 | DAO (0.44) | EP300KAT2BKAT8KDM5AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182210-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-05-28 | — | — | EP | claimed |
| EP-0182210-B1 | CEPHALOSPORIN DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |
| US-4742053-A | ANTIBIOTICS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-05-03 | — | — | US | disclosed |
| EP-0182210-A2 | Cephalosporin derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1986-05-28 | — | — | EP | disclosed |