Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.34 |
| ▸ | TUBB | P07437 | 3/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9827163 | 0.80 | MAPT (0.40) | LMNAMAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL9827285 | 0.80 | LMNA (0.44) | LMNAMAPTKMT2ACPB2NPC1 | |
| SCHEMBL7259699 | 0.80 | NOTUM (0.43) | LMNAKMT2AMAP4K4TP53SMN1; SMN2 | |
| SCHEMBL9826847 | 0.79 | CPB2 (0.38) | LMNAMAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL2174602 | 0.76 | KDM4E (0.48) | KMT2AKDM4E | |
| SCHEMBL7264439 | 0.76 | ALDH1A1 (0.44) | MAPTKMT2A | |
| SCHEMBL2730782 | 0.75 | CYP2A6 (0.54) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9826291 | 0.75 | KDM2B (0.45) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27911750 | 0.74 | KDM4E (0.47) | KMT2AKDM4E | |
| SCHEMBL7260043 | 0.73 | NCOA3 (0.51) | ALOX15MAPTKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282502-B1 | IMIDAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-05-15 | — | — | EP | claimed |
| EP-0282502-A1 | IMIDAZOLE DERIVATIVES. | SCHERING AG (DE) | 1988-09-21 | — | — | EP | claimed |
| WO-1988001268-A1 | IMIDAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1988-02-25 | — | — | WO | claimed |
| EP-0282502-B1 | IMIDAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-05-15 | — | — | EP | disclosed |
| EP-0282502-A1 | IMIDAZOLE DERIVATIVES. | SCHERING AG (DE) | 1988-09-21 | — | — | EP | disclosed |
| WO-1988001268-A1 | IMIDAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) | 1988-02-25 | — | — | WO | disclosed |