Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825690 | 0.90 | ALDH1A1 (0.39) | MEN1KMT2AMOGAT2KDM4ETDP1 | |
| SCHEMBL9825658 | 0.89 | DRD3 (0.34) | MOGAT2 | |
| SCHEMBL9827149 | 0.89 | ALDH1A1 (0.37) | MEN1KMT2AMOGAT2KDM4ETDP1 | |
| SCHEMBL9825542 | 0.87 | SMN1; SMN2 (0.37) | MEN1KMT2AMOGAT2 | |
| SCHEMBL9826186 | 0.87 | HRH3 (0.36) | MEN1KMT2AMOGAT2 | |
| SCHEMBL9827236 | 0.87 | ALDH1A1 (0.45) | MEN1KMT2AKDM4E | |
| SCHEMBL9825575 | 0.87 | ALDH1A1 (0.39) | CNR2MEN1KMT2AMOGAT2KDM4E | |
| SCHEMBL9826088 | 0.87 | L3MBTL1 (0.34) | MEN1KMT2AMOGAT2 | |
| SCHEMBL9827456 | 0.86 | ALDH1A1 (0.39) | MEN1KMT2AKDM4ETDP1 | |
| SCHEMBL9825803 | 0.85 | MCHR1 (0.34) | MEN1KMT2AMOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239815-B1 | SUBSTITUTED THIAZOLES AND OXAZOLES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1991-07-24 | — | — | EP | disclosed |
| EP-0239815-A1 | Substituted thiazoles and oxazoles, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1987-10-07 | — | — | EP | disclosed |