Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10645986 | 0.95 | ALDH1A1 (0.69) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| Rociclovir SCHEMBL29573658 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| Rociclovir SCHEMBL1228859 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL10817909 | 0.85 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL9583133 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL10528614 | 0.82 | KDM4E (0.64) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL9575559 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL9827507 | 0.81 | PDE3A (0.44) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL10648907 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL7750980 | 0.79 | KDM4E (0.79) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217207-B1 | 2-AMINO PURINES SUBSTITUTED IN POSITIONS 6 AND 9, THEIR USE, MEDICAMENTS CONTAINING THESE PURINES AND PROCESSES FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-10 | — | — | EP | claimed |
| EP-0217207-B1 | 2-AMINO PURINES SUBSTITUTED IN POSITIONS 6 AND 9, THEIR USE, MEDICAMENTS CONTAINING THESE PURINES AND PROCESSES FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-10 | — | — | EP | disclosed |
| EP-0217207-A1 | 2-Amino purines substituted in positions 6 and 9, their use, medicaments containing these purines and processes for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |