Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575434 | 0.89 | CYP1A2 (0.37) | ALDH1A1HPGDHSD17B10KDM4EADRA1A | |
| SCHEMBL9575565 | 0.85 | RPS6KA3 (0.39) | ALDH1A1HPGDHSD17B10KDM4EADRA1A | |
| SCHEMBL9019807 | 0.83 | PDE3A (0.32) | ALDH1A1PDE3ACYP3A4MEN1KMT2A | |
| SCHEMBL9575550 | 0.81 | ACHE (0.42) | ALDH1A1PDE3AHDAC6CYP3A4MEN1 | |
| SCHEMBL9827211 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HPGDHSD17B10KDM4EADRA1A | |
| Rociclovir SCHEMBL1228859 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10KDM4EADRA1A | |
| Rociclovir SCHEMBL29573658 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HPGDHSD17B10KDM4EADRA1A | |
| SCHEMBL9575441 | 0.79 | RPS6KA3 (0.35) | ALDH1A1HPGDHSD17B10KDM4EADRA1A | |
| SCHEMBL9019764 | 0.78 | PDE3A (0.38) | ALDH1A1PDE3ACYP3A4MEN1KMT2A | |
| SCHEMBL9019742 | 0.77 | ACHE (0.33) | ALDH1A1PDE3ACYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0464511-A2 | Process for the preparation of acyclic, substituted nucleosides and its intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |