Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.43 |
| ▸ | PPARG | P37231 | 13/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828248 | 0.87 | MAOB (0.50) | MAOBFFAR1PPARGRXRACYP3A4 | |
| SCHEMBL9828278 | 0.85 | MAOB (0.49) | MAOBFFAR1PPARGRXRACYP3A4 | |
| SCHEMBL10367689 | 0.82 | PPARG (0.60) | PPARGCYP3A4PPARA | |
| SCHEMBL9827179 | 0.78 | PPARG (0.44) | MAOBFFAR1PPARGRXRACYP3A4 | |
| SCHEMBL9458436 | 0.78 | PPARG (0.53) | MAOBFFAR1PPARGRXRACYP3A4 | |
| SCHEMBL8458527 | 0.78 | FFAR1 (0.54) | FFAR1PPARGRXRACYP3A4RARG | |
| SCHEMBL12521889 | 0.78 | MAOB (0.74) | MAOBFFAR1PPARGESR1PPARA | |
| SCHEMBL10364877 | 0.77 | PPARG (0.57) | MAOBFFAR1PPARGCYP3A4PPARA | |
| SCHEMBL9827679 | 0.75 | PPARG (0.57) | FFAR1PPARGRXRACYP3A4PPARA | |
| SCHEMBL12521870 | 0.75 | PPARG (0.61) | FFAR1PPARGRXRAPPARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0208420-B1 | THIAZOLIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-4775687-A | ANTIDIABETIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-10-04 | — | — | US | disclosed |
| EP-0208420-A1 | Thiazolidine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-01-14 | — | — | EP | disclosed |