Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 4/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.30 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9603012 | 0.87 | PDE4A (0.41) | ABCC9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9596470 | 0.87 | PDE4A (0.41) | ABCC9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7266970 | 0.84 | ABCC9 (0.41) | ABCC9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7269375 | 0.79 | PDE4A (0.42) | ABCC9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9300736 | 0.79 | PDE4A (0.41) | ABCC9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9220838 | 0.79 | PDE4A (0.41) | ABCC9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8088661 | 0.79 | PDE4A (0.47) | ABCC9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9300253 | 0.79 | PDE4A (0.40) | ABCC9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7277069 | 0.78 | PDE4A (0.39) | ABCC9PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8088704 | 0.78 | ABCC9 (0.40) | ABCC9PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413438-A1 | Benzopyran compounds | Beecham Group p.l.c. (GB) | 1991-02-20 | — | — | EP | claimed |
| EP-0413438-A1 | Benzopyran compounds | Beecham Group p.l.c. (GB) | 1991-02-20 | — | — | EP | disclosed |